Step 1

Lift the housing latch with your finger.

Step 2

Rotate the latch into unlocked position (empty dot).

Step 3

Lift the housing straight up and set it aside.

Step 4

Put the computer horizontally on side.

Step 5

Slide the PCIe retention latch to the right (into unlocked position).

Step 6

Remove the four captive Philips screws from the left clamp plate.

Step 7

Lift the clamp plate and remove it. 

Step 8

Unscrew another two captive screws this time from the right clamp plate using your fingers.

If they are tightened too much you can use a Philips screw driver to unscrew them.

Step 9

Remove the right clamp plate.

Step 10

Push the eject lever on the MPX module on it to reveal it.

Step 11

Pull the eject lever to disconnect the MPX module from the logic board.

Step 12

Use both hands to safely remove the MPX module from the computer.

Step 13

If your MPX module was was wider than the card you are going to install, then you can reinstall the two or three missing PCIe brackets to prevent dust getting into the chassis.

Step 14

Locate three power connector on the left side of the chassis.

Connectors 1-2 are 8-pin and provide 150W each.

Connectors 3-4 are also 8-pin and provide 150W each.

Connector 5-8 is single 6-pin and provide 75W.

Step 15

Connect the power cables.

For cards with a single 6-pin power connector you need to use connector 5-8 and a single mini 6-pin to large 6-pin power cable.

For cards with a single 8-pin power connector you need to use one of the connectors, either 1, 2, or 3, 4 with a single mini 8-pin to large 8-pin power cable.

For cards with 6+8-pin power connectors you need to use connector 5-8 with a a single mini 6-pin to large 6-pin power cable and one of the connectors, either 1, 2, or 3, 4 with a single mini 8-pin to large 8-pin power cable.

For cards with 8+8-pin power connectors you need to use both connectors, either 1 and 2, or 3 and 4 and two mini 8-pin to large 8-pin power cables.

For cards with 8+8+8-pin power connectors you need to use both connectors 1 and 2 or 3 and 4, and one additional connector, either 3 or 4, or 1 or 2 with three mini 8-pin to large 8-pin power cables.

Step 16

Insert the card to the slot 1 x16, or to slot 3 x16 if you plan to keep the MPX module.

Step 17

Connect the large ends of the power cables to the graphics card (order doesn't matter).

Step 18

Reinstall the right clamp plate and tighten the two captive screws with your fingers or Philips screwdriver.

Step 19

Reinstall the left clamp plate and tighten the four captive screws with Philips screwdriver.

Step 20

Slide the PCIe retention latch to the left (into locked position).

Step 21

Make sure the latch is in unlocked position and slowly slide back the housing over the frame.

Step 22

Rotate the latch into locked position (filled dot).

Step 23

Finally, lay the latch flat.

Step 24

You can use all the outputs on your graphics card.

PLEASE NOTE: A USB-C port is not Thunderbolt 3, so it won't support Thunderbolt 3 cables directly. You will need to use WJESOG USB-C to DisplayPort adapter with an extra USB-A connector and any DisplayPort to USB-C adapter to see something via USB-C port. In most cases it would be to just easier to use standard HDMI or DisplayPort connection.

Also when there is no MPX module inside the Mac Pro you won't be able to use Apple I/O card to drive displays.